A: Generally, they ask about your experience, your ideas and your ability to meet deadlines. They'll probably ask about your influences and your process, get a sense of your humor, that sort of thing.
In your case, I suspect they may get more specific. They'll probably want to know about your arms. They'll probably ask some questions about them. Questions like,
"How did you lose your arms?"
"How did losing your arms affect your cartooning?"
"Are robot arms a common prosthetic?"
"How powerful are your robot arms?"
"Could you crush a man with your robot arms?"
"Have you ever crushed a man with your robot arms, like an editor or publisher?"
Yup, they'll probably focus on that.
That might also ask if you can draw anything other than robot porn.